Title : Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines.

Pub. Date : 2005

PMID : 16165282






1 Functional Relationships(s)
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1 Prazosin attenuated stress-induced plasma IL-1beta and IL-6, but had no effect on tissue IL-1beta levels, while propranolol attenuated plasma IL-6 and blocked tissue IL-1beta elevation, and labetalol, which cannot cross the blood-brain barrier, attenuated plasma IL-1beta and IL-6, blocked pituitary IL-1beta, but had no effect on central tissue IL-1beta levels. Prazosin interleukin 1 beta Rattus norvegicus