Title : Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primarily by divalent metal transporter.

Pub. Date : 2006 Jan

PMID : 16140386






2 Functional Relationships(s)
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1 Furthermore, our study examined the effect of Fe status on astrocytic transferrin receptor (TfR) and divalent metal transporter (DMT-1) levels and their relationship to Mn uptake, as both have been implicated as putative Mn transporters. Iron transferrin receptor Rattus norvegicus
2 TfR levels were significantly increased (p<0.05) due to ID and decreased in astrocytes exposed to +Fe treatments. Iron transferrin receptor Rattus norvegicus