Title : Long-lived alphaMUPA transgenic mice show reduced SOD2 expression, enhanced apoptosis and reduced susceptibility to the carcinogen dimethylhydrazine.

Pub. Date : 2005 Dec

PMID : 16139868






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 To understand the molecular mechanisms underlying the increased apoptosis, we compared alphaMUPA and WT mice for parameters associated with SOD2 (MnSOD), a mitochondrial antioxidant enzyme that converts superoxide radicals into H(2)O(2) and is also known to inhibit apoptosis. Superoxides superoxide dismutase 2, mitochondrial Mus musculus
2 To understand the molecular mechanisms underlying the increased apoptosis, we compared alphaMUPA and WT mice for parameters associated with SOD2 (MnSOD), a mitochondrial antioxidant enzyme that converts superoxide radicals into H(2)O(2) and is also known to inhibit apoptosis. Superoxides superoxide dismutase 2, mitochondrial Mus musculus