Title : HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding.

Pub. Date : 2005 Nov 11

PMID : 16127177






1 Functional Relationships(s)
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Protein Name
Organism
1 We demonstrate that the Chromo domain of HP1 is mediating this binding and that phosphorylation of Ser(27) on H1.4 (S27/H1.4) prevents HP1 from binding. Serine chromobox 5 Homo sapiens