Title : Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same?

Pub. Date : 2005 Nov

PMID : 16118328






1 Functional Relationships(s)
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1 Therefore, a number of COX inhibitors were surveyed and it was determined that CYP2C9 plays a relatively minor role in the overall clearance (<or=20% of the dose) of sulindac, naproxen, ketoprofen, diclofenac, rofecoxib, and etoricoxib. Sulindac cytochrome P450 family 2 subfamily C member 9 Homo sapiens