Title : Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension.

Pub. Date : 2006 Jan

PMID : 16113050






1 Functional Relationships(s)
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1 An effective and selective dose of an iNOS inhibitor, L-N6-(1-iminoethyl)lysine (L-NIL), for chronic peroral treatment was first determined (8 mg/l in drinking water) by measuring exhaled NO concentration and systemic arterial pressure after LPS injection under ketamine+xylazine anesthesia. Ketamine nitric oxide synthase 2 Rattus norvegicus