Title : NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.

Pub. Date : 2005 Dec 1

PMID : 16105974






2 Functional Relationships(s)
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1 NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia. bafetinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 We have identified a specific dual Abl-Lyn inhibitor, NS-187 (elsewhere described as CNS-9), which is 25 to 55 times more potent than imatinib in vitro. bafetinib ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens