Title : Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus.

Pub. Date : 2005 Sep

PMID : 16101892






2 Functional Relationships(s)
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1 In addition, in glial cells, cholesterol is converted into pregnenolone by the P450 side-chain cleavage enzyme (P450scc), which is then metabolized to progesterone by 3beta-hydroxysteroid dehydrogenase, and subsequently reduced to 3alpha,5alpha-THP. Progesterone cytochrome P450, family 11, subfamily a, polypeptide 1 Rattus norvegicus
2 In addition, in glial cells, cholesterol is converted into pregnenolone by the P450 side-chain cleavage enzyme (P450scc), which is then metabolized to progesterone by 3beta-hydroxysteroid dehydrogenase, and subsequently reduced to 3alpha,5alpha-THP. Progesterone cytochrome P450, family 11, subfamily a, polypeptide 1 Rattus norvegicus