PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16088978-0 2005 AKT activation predicts outcome in breast cancer patients treated with tamoxifen. Tamoxifen 71-80 AKT serine/threonine kinase 1 Homo sapiens 0-3 16088978-3 2005 The present study was carried out to test the hypothesis that AKT activation mediates tamoxifen resistance in clinical breast cancer. Tamoxifen 86-95 AKT serine/threonine kinase 1 Homo sapiens 62-65 16088978-9 2005 The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. Tamoxifen 153-162 AKT serine/threonine kinase 1 Homo sapiens 43-46 16088978-9 2005 The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. Tamoxifen 153-162 AKT serine/threonine kinase 1 Homo sapiens 198-201 16088978-9 2005 The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. Tamoxifen 211-220 AKT serine/threonine kinase 1 Homo sapiens 43-46 16088978-9 2005 The data presented here show that the PI3K/AKT/mTOR pathway is associated with relapse and death in ERalpha-positive breast cancer patients treated with tamoxifen, supporting in vitro evidence that AKT mediates tamoxifen resistance. Tamoxifen 211-220 AKT serine/threonine kinase 1 Homo sapiens 198-201