Title : Kinetic analysis of the polymerization and depolymerization of beta(2)-microglobulin-related amyloid fibrils in vitro.

Pub. Date : 2005 Nov 10

PMID : 16084781






1 Functional Relationships(s)
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1 Very recently, low concentrations of 2,2,2-trifluoroethanol (TFE) and the sub-micellar concentration of sodium dodecyl sulfate, a model for anionic phospholipids, have been reported to cause the extension of Abeta(2)M amyloid fibrils at a neutral pH, inducing partial unfolding of beta(2)-m and stabilization of the fibrils. Sodium Dodecyl Sulfate beta-2-microglobulin Homo sapiens