Pub. Date : 2006 Apr 15
PMID : 16084549
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Activations of c-fos/c-jun signaling are involved in the modulation of hypothalamic superoxide dismutase (SOD) and neuropeptide Y (NPY) gene expression in amphetamine-mediated appetite suppression. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
2 | Results showed that AMPH treatment decreased food intake, which was correlated with changes of NPY mRNA level, but increased c-fos, c-jun and superoxide dismutase (SOD) mRNA levels in hypothalamus. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
3 | It was suggested that c-fos/c-jun signaling might involve in the central regulation of AMPH-mediated feeding suppression via the modulation of NPY gene expression. | Amphetamine | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |