Title : EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.

Pub. Date : 2005 Sep 2

PMID : 16053920






1 Functional Relationships(s)
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1 We previously reported that in the HT29 human colon cancer cell line EGCG, the major biologically active component of green tea, inhibits activation of the RTKs EGFR, HER2, and HER3, and that this is associated with inhibition of multiple downstream signaling pathways. epigallocatechin gallate epidermal growth factor receptor Homo sapiens