Pub. Date : 2005 Oct 14
PMID : 16049007
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, H(2)O(2) treatment not only induced GST expression but also increased intracellular maspin/GST interaction, which was inversely correlated with the level of ROS generation. | Reactive Oxygen Species | glutathione S-transferase kappa 1 | Homo sapiens |
| 2 | Furthermore, the maspin effect on ROS generation was completely abolished by a GST inhibitor, indicating an essential role of GST in maspin-mediated cellular response to oxidative stress. | Reactive Oxygen Species | glutathione S-transferase kappa 1 | Homo sapiens |
| 3 | Furthermore, the maspin effect on ROS generation was completely abolished by a GST inhibitor, indicating an essential role of GST in maspin-mediated cellular response to oxidative stress. | Reactive Oxygen Species | glutathione S-transferase kappa 1 | Homo sapiens |
| 4 | Together, our data suggest a new mechanism by which maspin, through its direct interaction with GST, may inhibit oxidative stress-induced ROS generation and vascular endothelial growth factor A induction, thus preventing further adverse effects on tumor genetics and stromal reactivity. | Reactive Oxygen Species | glutathione S-transferase kappa 1 | Homo sapiens |