Pub. Date : 2005 Aug
PMID : 16045972
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To test this hypothesis, we evaluated the effects of chronic donepezil, nicotine and haloperidol on expression levels of 5-HT2A mRNA and 5-HT2A receptor density in select brain regions. | Nicotine | 5-hydroxytryptamine (serotonin) receptor 2A | Mus musculus |
| 2 | The cortex was the only area where donepezil, nicotine and haloperidol significantly reduced the 5-HT2A receptor density. | Nicotine | 5-hydroxytryptamine (serotonin) receptor 2A | Mus musculus |
| 3 | The results suggest that the anti-tic properties of donepezil, nicotine and haloperidol in this paradigm might be due to antagonism of cortical 5-HT2A receptors. | Nicotine | 5-hydroxytryptamine (serotonin) receptor 2A | Mus musculus |