Title : [Dynamic evolution of MMP-2 gene expression and its enzymatic activities in experimental liver fibrosis].

Pub. Date : 2005 Jul

PMID : 16042886






3 Functional Relationships(s)
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1 RESULTS: In the model group the hepatic MMP-2 mRNA expression started to increase 10 days after DMN administration and remained at a much higher level than in the normal group throughout the study period, while TIMP-2 mRNA expression started to be lower than in the normal group 17 days after DMN administration and reached the lowest level on the 28th day. Dimethylnitrosamine matrix metallopeptidase 2 Rattus norvegicus
2 RESULTS: In the model group the hepatic MMP-2 mRNA expression started to increase 10 days after DMN administration and remained at a much higher level than in the normal group throughout the study period, while TIMP-2 mRNA expression started to be lower than in the normal group 17 days after DMN administration and reached the lowest level on the 28th day. Dimethylnitrosamine matrix metallopeptidase 2 Rattus norvegicus
3 TIMP-2/MMP-2 began to be lower by several days than that of the normal group after DMN administration through the remaining study period. Dimethylnitrosamine matrix metallopeptidase 2 Rattus norvegicus