Title : Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice.

Pub. Date : 2005 Nov

PMID : 16037401






1 Functional Relationships(s)
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1 Gene expression analysis showed that CIH upregulated multiple genes controlling 1) cholesterol and fatty acid biosynthesis [malic enzyme and acetyl coenzyme A (CoA) synthetase], 2) predominantly fatty acid biosynthesis (acetyl-CoA carboxylase and stearoyl-CoA desaturases 1 and 2), and 3) triglyceride and phospholipid biosynthesis (mitochondrial glycerol-3-phosphate acyltransferase). cih stearoyl-Coenzyme A desaturase 1 Mus musculus