Title : Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine.

Pub. Date : 2005 Jul

PMID : 16022506






1 Functional Relationships(s)
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Protein Name
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1 Trapping of the guanine lesions by the base excision repair enzymes hOGG1 and mNEIL2 showed nearly exclusive trapping by mNEIL2, suggesting that 8-oxoG was not the major lesion but rather a lesion recognized by mNEIL2 such as Sp. Guanine 8-oxoguanine DNA glycosylase Homo sapiens