Title : Modulation of nicotinic acetylcholine receptor channel by pH: a difference in pH sensitivity of Torpedo and mouse receptors expressed in Xenopus oocytes.

Pub. Date : 1992 Apr

PMID : 1600556






1 Functional Relationships(s)
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1 The peak current responses of four mouse-Torpedo nAChR hybrids consisting of three Torpedo subunits and one mouse nAChR subunit displayed similar pH profiles at acidic pH, with a pKa of 6.0 to 6.5, which lay between the pKa 5.6 for mouse and the pKa 7.0 for Torpedo nAChRs. nachrs cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus