Title : Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis.

Pub. Date : 2005 Jul 12

PMID : 15996096






1 Functional Relationships(s)
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1 The X-ray structure of human hPKM2 complexed with Mg(2+), K(+), the inhibitor oxalate, and the allosteric activator fructose 1,6-bisphosphate (FBP) has been determined to a resolution of 2.82 A. Oxalates pyruvate kinase M1/2 Homo sapiens