Title : Leptin enhances TNF-alpha production via p38 and JNK MAPK in LPS-stimulated Kupffer cells.

Pub. Date : 2005 Aug 12

PMID : 15979653






1 Functional Relationships(s)
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1 SB203580 and JNK inhibitor I, specific inhibitors of P38 and JNK, inhibited TNF-alpha production in KCs but PD98059, an inhibitor of the ERK pathway, did not affect TNF-alpha production by KCs. SB 203580 mitogen-activated protein kinase 8 Rattus norvegicus