Title : Elevated serum GGT concentrations predict reduced insulin sensitivity and increased intrahepatic lipids.

Pub. Date : 2005 Apr

PMID : 15952086






3 Functional Relationships(s)
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1 Serum GGT was positively correlated with two-hour glucose during oGTT (r = 0.15, p < 0.0001) and negatively correlated with insulin sensitivity from oGTT (r = -0.31, p < 0.0001) and clamp (r = -0.27, p < 0.0001). Glucose gamma-glutamyltransferase light chain family member 3 Homo sapiens
2 In conclusion, elevated serum GGT levels predict glucose intolerance probably via insulin resistance rather than beta-cell dysfunction. Glucose gamma-glutamyltransferase light chain family member 3 Homo sapiens
3 In the absence of overt liver disease, elevated serum GGT concentrations may point the clinician to incipient disturbances in the glucose metabolism. Glucose gamma-glutamyltransferase light chain family member 3 Homo sapiens