Pub. Date : 2005 Jun 30
PMID : 15950210
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In a previous study of quinone toxicity, this quinone, whose actions have been exclusively attributed to reactive oxygen species (ROS) generation, caused a reduction in the glycolytic activity of GAPDH under aerobic and anaerobic conditions, indicating indirect and possible direct actions on this enzyme. | quinone | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 2 | In a previous study of quinone toxicity, this quinone, whose actions have been exclusively attributed to reactive oxygen species (ROS) generation, caused a reduction in the glycolytic activity of GAPDH under aerobic and anaerobic conditions, indicating indirect and possible direct actions on this enzyme. | quinone | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 3 | This quinone, which is not considered an electrophile, inhibited GAPDH in a time-dependent manner, consistent with irreversible modification and comparable to the electrophilic actions of 1,4-benzoquinone (1,4-BQ). | quinone | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |
| 4 | This quinone, which is not considered an electrophile, inhibited GAPDH in a time-dependent manner, consistent with irreversible modification and comparable to the electrophilic actions of 1,4-benzoquinone (1,4-BQ). | quinone | glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens |