Title : Intramolecular hydroamination of alkynes catalyzed by Pd(PPh3)4/triphenylphosphine under neutral conditions.

Pub. Date : 2005 Jun 10

PMID : 15932337






2 Functional Relationships(s)
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1 The intramolecular hydroamination of alkynes tethered with amino group 1 in the presence of catalytic amounts of Pd(PPh3)4 and PPh3 in benzene at 100 degrees C proceeded smoothly without the use of any additional acid source to afford five- and six-membered nitrogen heterocycles 2 in good to excellent yields. Nitrogen caveolin 1 Homo sapiens
2 The intramolecular hydroamination of alkynes tethered with amino group 1 in the presence of catalytic amounts of Pd(PPh3)4 and PPh3 in benzene at 100 degrees C proceeded smoothly without the use of any additional acid source to afford five- and six-membered nitrogen heterocycles 2 in good to excellent yields. Nitrogen caveolin 1 Homo sapiens