Title : Altered expression of p53, Bcl-2 and Bax induced by microcystin-LR in vivo and in vitro.

Pub. Date : 2005 Aug

PMID : 15922382






2 Functional Relationships(s)
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1 The results show that MC-LR can increase the expression of p53 and Bax significantly both in vivo and in vitro, however, MC-LR can only decrease the expression of Bcl-2 significantly in vitro and there is no difference observed in vivo. cyanoginosin LR BCL2 associated X, apoptosis regulator Rattus norvegicus
2 It can be concluded that the expression of p53, Bcl-2 and Bax are involved in the regulation of MC-LR induced apoptosis. cyanoginosin LR BCL2 associated X, apoptosis regulator Rattus norvegicus