Title : Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis.

Pub. Date : 2005 Jul 22

PMID : 15917250






1 Functional Relationships(s)
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1 Only Yes and JNK activation were sensitive to N-acetylcysteine, inhibitors of NADPH oxidase, PKCzeta, or sphingomyelinase, indicating that the CD95L-induced ROS response is upstream of Yes and JNK but not of Fyn and c-Src activation. Acetylcysteine mitogen-activated protein kinase 8 Rattus norvegicus