Title : Biological activity of recombinant chicken interleukin-6 in chicken hybridoma cells.

Pub. Date : 2005 Jun 15

PMID : 15910996






2 Functional Relationships(s)
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1 Cell proliferation and tyrosine phosphorylation of signal transducer and activator of transcription-3 (STAT3) were induced by rchIL-6 in the IL-6-dependent murine hybridoma cell line MH60, whereas the recombinant protein exhibited no significant cell proliferation activity in chicken hybridoma cells but induced antibody production and tyrosine phosphorylation of STAT3. Tyrosine interleukin 6 Mus musculus
2 Cell proliferation and tyrosine phosphorylation of signal transducer and activator of transcription-3 (STAT3) were induced by rchIL-6 in the IL-6-dependent murine hybridoma cell line MH60, whereas the recombinant protein exhibited no significant cell proliferation activity in chicken hybridoma cells but induced antibody production and tyrosine phosphorylation of STAT3. Tyrosine interleukin 6 Mus musculus