Title : Neuroprotective effects of novel small peptides in vitro and after brain injury.

Pub. Date : 2005 Sep

PMID : 15907950

1 Functional Relationships(s)
Compound Name
Protein Name
1 DNA microarray studies following fluid percussion induced traumatic brain injury (TBI) in rats showed that treatment with one of these dipeptides after injury significantly down-regulated expression of mRNAs for cell cycle proteins, aquaporins, cathepsins and calpain in ipsilateral cortex and/or hippocampus, while up-regulating expression of brain-derived neurotrophic factor, hypoxia-inducible factor and several heat-shock proteins. Dipeptides brain-derived neurotrophic factor Rattus norvegicus