Title : 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-kappaB and ERK/MAPK.

Pub. Date : 2005 Oct 1

PMID : 15901486






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A pharmacological inhibitor of ERK aggravated the 4-OHE2-induced cytotoxicity, supporting the pivotal role of ERK in protecting against catechol estrogen-induced oxidative cell death. catechol mitogen-activated protein kinase 1 Homo sapiens
2 A pharmacological inhibitor of ERK aggravated the 4-OHE2-induced cytotoxicity, supporting the pivotal role of ERK in protecting against catechol estrogen-induced oxidative cell death. catechol mitogen-activated protein kinase 1 Homo sapiens