Title : Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.

Pub. Date : 2005 Jul 15

PMID : 15899885






1 Functional Relationships(s)
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1 We show that addition of cholesterol or 25-hydroxycholesterol to microsomal membranes in vitro blocks Sar1-dependent binding of the Sec23/24 complex to Scap, the SREBP escort protein. 25-hydroxycholesterol SREBF chaperone Homo sapiens