Title : Lower birth weight as a critical effect of chlorpyrifos: a comparison of human and animal data.

Pub. Date : 2005 Jun

PMID : 15896443






4 Functional Relationships(s)
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1 Chlorpyrifos is an irreversible inhibitor of cholinesterase (ChE), and inhibition of ChE is believed to be the most sensitive effect in all animal species evaluated and in humans. Chlorpyrifos butyrylcholinesterase Homo sapiens
2 Chlorpyrifos is an irreversible inhibitor of cholinesterase (ChE), and inhibition of ChE is believed to be the most sensitive effect in all animal species evaluated and in humans. Chlorpyrifos butyrylcholinesterase Homo sapiens
3 We analyze the available information from epidemiology studies and animal studies in order to identify the relative sensitivity of decreased birth weight and inhibition of ChE from exposure to chlorpyrifos. Chlorpyrifos butyrylcholinesterase Homo sapiens
4 Moreover, the critical effect for chlorpyrifos still appears to be cholinesterase inhibition. Chlorpyrifos butyrylcholinesterase Homo sapiens