Pub. Date : 2005 Feb
PMID : 15895823
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice. | Iron | amyloid beta (A4) precursor protein | Mus musculus |
2 | This study confirms the presence of iron, co-localized with Abeta plaques, in PS/APP mouse brain, using Perls" stain for Fe3+ supplemented by 3,3"-diaminobenzidine (DAB) and Abeta immunohistochemistry in histological brains sections fixed with formalin or methacarn. | Iron | amyloid beta (A4) precursor protein | Mus musculus |
3 | This study confirms the presence of iron, co-localized with Abeta plaques, in PS/APP mouse brain, using Perls" stain for Fe3+ supplemented by 3,3"-diaminobenzidine (DAB) and Abeta immunohistochemistry in histological brains sections fixed with formalin or methacarn. | Iron | amyloid beta (A4) precursor protein | Mus musculus |
4 | The presence of iron in beta-amyloid plaques in PS/APP transgenic mice, a model of Alzheimer"s disease (AD) pathology, may explain previous reports of reductions of transverse relaxation time (T2) in MRI studies and represent the source of the intrinsic Abeta plaque MR contrast in this model. | Iron | amyloid beta (A4) precursor protein | Mus musculus |