Title : A brainstem substrate for analgesia elicited by intraoral sucrose.

Pub. Date : 2005

PMID : 15893646






3 Functional Relationships(s)
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1 Fos immunohistochemistry was used to identify brainstem neurons activated by a brief (90 s) intraoral infusion of a small volume (90 microl, 0.2M) of sucrose or a salt solution (0.1 M ammonium chloride) in 10-day-old rat pups. Sucrose Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Compared with control groups (intact, cannula, distilled water), both sucrose and ammonium chloride induced Fos expression in the rostral nucleus tractus solitarius, the first relay in the ascending gustatory pathway. Sucrose Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 Sucrose also elicited Fos expression in several brainstem areas associated with centrally mediated analgesia, including the periaqueductal gray and the nucleus raphe magnus. Sucrose Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus