Pub. Date : 2005 Jun
PMID : 15878779
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It is hypothesized that, through the antagonism of cannabinoid CB1 receptors located on inhibitory and excitatory axon terminals targeting the midbrain dopamine neurons, the effects of the endocannabinoids are occluded. | Dopamine | cannabinoid receptor 1 | Homo sapiens |
| 2 | The data from these studies therefore suggest that the endocannabinoid system and the CB1 receptors located in the ventral mesencephalon may play an important role in regulating drug reward processes, and that this substrate is recruited whenever dopamine neuron activity is increased. | Dopamine | cannabinoid receptor 1 | Homo sapiens |