Title : Epigenetic regulation of vitamin D hydroxylase expression and activity in normal and malignant human prostate cells.

Pub. Date : 2005 Feb

PMID : 15860259






1 Functional Relationships(s)
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1 Treatment of PNT-2 cells with the methylation inhibitor 5-aza-2"-deoxycytidine together with the deacetylation inhibitor trichostatin A resulted in elevation of both CYP27B1 and CYP24 mRNA expression demonstrating that even in normal human prostate cells expression of Vitamin D hydroxylases may be under epigenetic control. Decitabine cytochrome P450 family 24 subfamily A member 1 Homo sapiens