Title : Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

Pub. Date : 2005 Jul

PMID : 15855407






1 Functional Relationships(s)
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1 Pretreatment of cells with N-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline (H-89), an inhibitor of protein kinase A (PKA), attenuated the PGE2-mediated phosphorylation of CREB in EP2-expressing cells, but not in EP4-expressing cells. n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline prostaglandin E receptor 2 Homo sapiens