Title : Nitric oxide protects against ischemic acute renal failure through the suppression of renal endothelin-1 overproduction.

Pub. Date : 2004 Nov

PMID : 15838347






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1 In contrast, N(G)-nitro-L-arginine methyl ester (1 or 10 mg/kg, intravenously) pretreatment dose-dependently aggravated renal injuries of acute renal failure rats, and the effect is accompanied by further increase in the renal endothelin-1 contents. NG-Nitroarginine Methyl Ester endothelin 1 Rattus norvegicus