Title : HMG-CoA reductase inhibitors reduce I kappa B kinase activity induced by oxidative stress in monocytes and vascular smooth muscle cells.

Pub. Date : 2005 May

PMID : 15821443






1 Functional Relationships(s)
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1 In THP-1 and cultured VSMC, O2- caused an increase in NF-kappa B activation (P < 0.05) that was correlated with inhibitory I kappa B-alpha degradation. Superoxides nuclear factor kappa B subunit 1 Homo sapiens