Title : Hepatic expression of S32A/S36A IkappaBalpha does not reduce postischemic liver injury.

Pub. Date : 2005 Apr

PMID : 15820254






1 Functional Relationships(s)
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1 CONCLUSIONS: The data demonstrate that the pathway of NF-kappaB activation involving serine phosphorylation of IkappaBalpha is not the primary mechanism for induction of liver inflammation after ischemia/reperfusion and suggest that alternative pathways, such as tyrosine phosphorylation of IkappaBalpha, may be essential for the postischemic response in liver. Tyrosine nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus