Title : Role of poly(ADP-ribose) polymerase activity in imatinib mesylate-induced cell death.

Pub. Date : 2005 Jun

PMID : 15818402






1 Functional Relationships(s)
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1 The effect of imatinib on PAR can be mimicked by inhibition of phosphatidylinositol 3-kinase (PI3-K) implicating a central role of the PI3-K pathway in Bcr-Abl-mediated inhibition of PAR. Imatinib Mesylate phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens