Title : Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1.

Pub. Date : 2005 May

PMID : 15813748






1 Functional Relationships(s)
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1 Using three different approaches [expression of an inactive (E794K) GBF1 mutant, expression of the ARF1 (T31N) mutant with decreased affinity for GTP and Brefeldin A treatment], we show that GBF1 is stabilized on membranes when in a complex with ARF-GDP. Guanosine Diphosphate ADP ribosylation factor 1 Homo sapiens