Title : Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets.

Pub. Date : 2005 Jul 15

PMID : 15811957






4 Functional Relationships(s)
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1 Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Tyrosine coagulation factor II, thrombin Homo sapiens
2 Thrombin has been known to cause tyrosine phosphorylation of protein kinase C delta (PKCdelta) in platelets, but the molecular mechanisms and function of this tyrosine phosphorylation is not known. Tyrosine coagulation factor II, thrombin Homo sapiens
3 Thrombin has been known to cause tyrosine phosphorylation of protein kinase C delta (PKCdelta) in platelets, but the molecular mechanisms and function of this tyrosine phosphorylation is not known. Tyrosine coagulation factor II, thrombin Homo sapiens
4 We conclude that thrombin causes tyrosine phosphorylation of PKCdelta in a calcium- and Src-family kinase-dependent manner in platelets, with functional implications in thromboxane A2 generation. Tyrosine coagulation factor II, thrombin Homo sapiens