Title : Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.

Pub. Date : 2005 May 13

PMID : 15809062






1 Functional Relationships(s)
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1 In addition, the PI3 kinase inhibitor, LY294002, upregulates IGFBP-3 expression but downregulates IGF-I and IGF-II, indicating that PTEN controls IGFBP-3 and IGFs by an Akt-dependent pathway. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one phosphatase and tensin homolog Homo sapiens