Title : Elevated dietary sodium intake exacerbates myocardial hypertrophy associated with cardiac-specific overproduction of angiotensin II.

Pub. Date : 2004 Dec

PMID : 15806712






3 Functional Relationships(s)
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1 Elevated dietary sodium intake exacerbates myocardial hypertrophy associated with cardiac-specific overproduction of angiotensin II. Sodium angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus
2 CONCLUSION: This study demonstrates that, where there is a pre-existing genetic condition of Ang II-dependent cardiac hypertrophy, the pro-growth effect of elevated dietary sodium is selectively augmented. Sodium angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus
3 The cellular mechanistic bases for this specific ANG II-dietary sodium interaction remain to be elucidated. Sodium angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus