Pub. Date : 2004 Dec
PMID : 15801068
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Osteocalcin synthesis by human osteoblasts from normal and osteoarthritic bone after vitamin D3 stimulation. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |
| 2 | In this study we correlated osteocalcin production from human osteoblasts isolated from healthy and osteoarthritic subjects to the degree of cartilage damage, before and after stimulation with 1,25(OH)2-vitamin D3, the active metabolite of vitamin D3. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |
| 3 | We determined the osteocalcin production in normal and osteoarthritic osteoblasts from maximal and minimal cartilage damage areas both under basal conditions and after vitamin D3 stimulation. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |
| 4 | The response of osteoblasts to vitamin D3 stimulation appeared to be proportional to the degree of joint damage, as the vitamin D3-induced increase in osteocalcin is proportionally greater in maximally damaged osteoblasts compared to minimally damaged ones. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |
| 5 | The response of osteoblasts to vitamin D3 stimulation appeared to be proportional to the degree of joint damage, as the vitamin D3-induced increase in osteocalcin is proportionally greater in maximally damaged osteoblasts compared to minimally damaged ones. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |
| 6 | Thus, after vitamin D3 stimulation, a significant increase in osteocalcin production by maximally damaged osteoblasts compared to the minimally damaged ones was observed. | Cholecalciferol | bone gamma-carboxyglutamate protein | Homo sapiens |