Title : Stereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro.

Pub. Date : 2005 Jan

PMID : 15788366






1 Functional Relationships(s)
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1 The estimated K(i) values determined for CYP2C19-catalysed S-mephenytoin 4"-hydroxylation were 0.6, 6.1, 3.4 and 5.7 microM for S-lansoprazole, R-lansoprazole, S-omeprazole and R-omeprazole, respectively. Dexlansoprazole cytochrome P450 family 2 subfamily C member 19 Homo sapiens