Pub. Date : 2005 Apr
PMID : 15773923
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson"s disease. | Dopamine | tyrosinase | Homo sapiens |
| 2 | Whether tyrosinase is beneficial or detrimental to neurons is unclear; whilst the enzyme activity of tyrosinase generates dopamine-quinones and other oxidizing compounds, NM may form a sink for such radical species. | Dopamine | tyrosinase | Homo sapiens |
| 3 | In cell culture systems, expression of tyrosinase increases neuronal susceptibility to oxidizing conditions, including dopamine itself. | Dopamine | tyrosinase | Homo sapiens |