Pub. Date : 2005 Jan
PMID : 15771232
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Significant increases (3- to 6-fold) in amodiaquine N-deethylase (a functional probe for CYP2C8 activity) also were observed with clofibric acid, fenofibric acid, and rifampin, in agreement with the mRNA finding. | fenofibric acid | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |
| 2 | CONCLUSIONS: In human hepatocytes, both fenofibric acid and clofibric acid are inducers of CYP3A4 and CYP2C8. | fenofibric acid | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |