Title : Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium.

Pub. Date : 2005 Jul 1

PMID : 15769249






2 Functional Relationships(s)
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1 Cells in which PLD activity is inhibited by butan-1-ol show a complete loss of actin-based structures, accompanied by relocalization of F-actin into small clusters, and eventually the nucleus, without a visible fall in levels of F-actin. Butanols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 Addition of exogenous phosphatidic acid reverses the effects of butan-1-ol, confirming that these effects are caused by inhibition of PLD. Butanols glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens