Pub. Date : 2005 Jun
PMID : 15755907
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons. | Ethanol | RE1 silencing transcription factor | Homo sapiens |
| 2 | Treatment of cultured cortical neurons with 100 mM ethanol for 5 days caused a significant decrease in the NRSF mRNA and protein levels, NRSF/NRSE binding activity, and an increase in the promoter activity. | Ethanol | RE1 silencing transcription factor | Homo sapiens |
| 3 | Treatment of cultured cortical neurons with 100 mM ethanol for 5 days caused a significant decrease in the NRSF mRNA and protein levels, NRSF/NRSE binding activity, and an increase in the promoter activity. | Ethanol | RE1 silencing transcription factor | Homo sapiens |
| 4 | Therefore, our studies suggest that NRSF is a negative regulator of NR2B expression and may contribute to the ethanol-induced up-regulation of the NR2B gene in fetal cortical neurons. | Ethanol | RE1 silencing transcription factor | Homo sapiens |