Title : Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells.

Pub. Date : 2005 Apr 29

PMID : 15741166






1 Functional Relationships(s)
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1 Presently, small interference (si) RNA constructs were used to investigate the role of human BVR in sodium arsenite (As)-mediated induction of HO-1 and in cytoprotection against apoptosis. sodium arsenite heme oxygenase 1 Homo sapiens